KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSL2
All Species:
21.82
Human Site:
S440
Identified Species:
68.57
UniProt:
Q9HCI7
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCI7
NP_001138889.1
577
62541
S440
A
V
K
E
K
I
P
S
H
H
F
M
P
G
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542793
838
90536
S701
T
V
K
E
K
I
P
S
H
H
F
M
P
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q69ZF8
577
62519
S440
A
V
K
E
K
M
P
S
H
H
F
M
P
G
S
Rat
Rattus norvegicus
XP_001071576
577
62434
S440
A
V
K
E
K
I
P
S
H
H
F
M
P
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518890
532
56142
T406
M
P
G
S
P
T
K
T
V
Y
K
K
P
Q
E
Chicken
Gallus gallus
XP_426675
579
62234
S442
K
A
K
E
K
V
P
S
S
N
V
M
P
G
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001156785
598
64113
T457
K
M
K
D
R
I
L
T
S
A
L
I
P
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796886
364
40810
T238
R
K
E
S
E
D
S
T
F
D
Y
E
K
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
68.1
N.A.
98.9
98.6
N.A.
74.6
83.9
N.A.
59.3
N.A.
N.A.
N.A.
N.A.
20.1
Protein Similarity:
100
N.A.
N.A.
68.3
N.A.
99.6
99.4
N.A.
82.5
91.5
N.A.
72.5
N.A.
N.A.
N.A.
N.A.
33.2
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
93.3
100
N.A.
6.6
60
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
100
100
N.A.
20
73.3
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
38
13
0
0
0
0
0
0
0
13
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
13
0
13
0
0
0
13
0
0
0
0
0
% D
% Glu:
0
0
13
63
13
0
0
0
0
0
0
13
0
13
13
% E
% Phe:
0
0
0
0
0
0
0
0
13
0
50
0
0
0
0
% F
% Gly:
0
0
13
0
0
0
0
0
0
0
0
0
0
75
0
% G
% His:
0
0
0
0
0
0
0
0
50
50
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
50
0
0
0
0
0
13
0
0
0
% I
% Lys:
25
13
75
0
63
0
13
0
0
0
13
13
13
0
13
% K
% Leu:
0
0
0
0
0
0
13
0
0
0
13
0
0
0
0
% L
% Met:
13
13
0
0
0
13
0
0
0
0
0
63
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% N
% Pro:
0
13
0
0
13
0
63
0
0
0
0
0
88
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% Q
% Arg:
13
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
25
0
0
13
63
25
0
0
0
0
0
75
% S
% Thr:
13
0
0
0
0
13
0
38
0
0
0
0
0
0
0
% T
% Val:
0
50
0
0
0
13
0
0
13
0
13
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
13
13
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _